Stinging nettle root has been shown to prevent the conversion of testosterone into dihydrotestosterone (DHT), which will significantly increase the amount of free testosterone in your body… if you’re a rat. Nettle is a powerful plant, which in high doses, can cause multiple issues. Rau O, Wurglics M, Dingermann T, Abdel-Tawab M, Schubert-Zsilavecz M. Screening of herbal extracts for activation of the human peroxisome proliferator-activated receptor. This information may not fit your specific health circumstances. Safety and efficacy in the treatment of lower urinary tract symptoms. Pak.J.Biol.Sci. Konrad L, Muller HH, Lenz C, et al. Sokeland J, Albrecht J. The efficacy of Prrrikweg gel in the treatment of insect bites: a double-blind, placebo-controlled clinical trial. Some research suggests that taking an oral extract of stinging nettle with a non-steroidal anti-inflammatory drug (NSAID) can help people lower their dosage of the NSAID. The following doses have been studied in scientific research: View abstract. Urologiia. Follow the directions on the package label or use the lowest effective dose. The dose of your diabetes medication might need to be changed. [Combined extract of Sabal palm and nettle in the treatment of patients with lower urinary tract symptoms in double blind, placebo-controlled trial]. View abstract. Urologe A 1997;36:327-33. Czarnetzki, B. M., Thiele, T., and Rosenbach, T. Immunoreactive leukotrienes in nettle plants (Urtica urens). Taking stinging nettle along with medications for high blood pressure might cause your blood pressure to go too low. The dose of your warfarin (Coumadin) might need to be changed. View abstract. View abstract. 120mg of Stinging Nettle (root) taken three times a day (totalling 360mg) is … Altern.Med.Rev. Traditionally, nettle is used topically on wounds and it looks like science backs this … Kraus R, Spiteller G, and Bartsch W. [(10E,12Z)-9-Hydroxy-10,12-octadecadienoic acid, an aromatase inhibitor from roots of Urtica dioica]. Quercetin. Taking stinging nettle might decrease how well the body gets rid of lithium. Hartmann RW, Mark M, and Soldati F. Inhibition of a 5 a-reductase and aromatase by PHL-00801 (Prostatonin®), a combination of PY102 (Pygeum africanum) and UR 102 (Urtica dioica) extracts. Prostate 1993;22(1):43-51. Reproduction in whole or in part without permission is prohibited. By helping the blood clot, stinging nettle might decrease the effectiveness of warfarin (Coumadin). dosages & applications of stinging nettle To use as an infusion (tea): Pour one cup boiling water over 2-3 tablespoons leaves or plant and steep for 10-20 minutes or until desired temperature. Proc West Pharmacol Soc 2003;46:153-5. View abstract. Jacquet, A., Girodet, P. O., Pariente, A., Forest, K., Mallet, L., and Moore, N. Phytalgic, a food supplement, vs placebo in patients with osteoarthritis of the knee or hip: a randomised double-blind placebo-controlled clinical trial. Stay Connected With Dr. Weil - Get Free Newsletters Right In Your Inbox, Information on this website is provided for informational purposes only and is not intended as a substitute for the advice provided by your physician or other healthcare professional. Prep Biochem Biotechnol. Some sedative medications include clonazepam (Klonopin), lorazepam (Ativan), phenobarbital (Donnatal), zolpidem (Ambien), and others. 770 mg dried extract orally twice daily. Vitamins and Supplements to Avoid with Hepatitis C. Quiz: What Do You Know About Vitamin B12 Deficiency? Rhodes, L., Primka, R. L., Berman, C., Vergult, G., Gabriel, M., Pierre-Malice, M., and Gibelin, B. Sedative medications (CNS depressants) interacts with STINGING NETTLE. Huber, R., Bross, F., Schempp, C., and Grundemann, C. Arnica and stinging nettle for treating burns - a self-experiment. 1990;91(1):43-46. Some research shows that taking stinging nettle daily for 2-12 months improves urinary tract symptoms and the flow of urine in people with BPH. The herb has a medicinal history stretching back to the ancient Greeks who used it as a diuretic and to relieve joint pain. There are no recommendations for correct dosage of stinging nettle for increasing testosterone. Available Forms of Nettle Urtica. Effects of Various Doses of Selenite on Stinging Nettle (Urtica dioica L.). Studies suggest that stinging nettle may improve urinary flow and relieve other BPH symptoms including incomplete emptying of the bladder, post urination dripping, and the constant urge to urinate (bladder irritability). View abstract. Diuretic– increases flow of urine and kidney filtrati… (Abstract). Nettle leaf tea is a wonderful way to give your dog relief from the constant itch of dry skin or flea bites. View abstract. Phytomedicine 1995;4:287-290. 2007;14(7-8):568-579. For the root extract, you should ideally aim for 100mg to 120mg taken 3 times per day for a total of 300mg to 360mg. The dose largely depends on the specific product but is typically one or two capsules every two to four hours as needed – follow label instructions. Men C, Wang M, Aiyireti M, Cui Y. Reviewed by Russell Greenfield, M.D., August, 2016. The effect of stinging nettle on A1c in people with diabetes is unclear. Riehemann, K., Behnke, B., and Schulze-Osthoff, K. Plant extracts from stinging nettle (Urtica dioica), an antirheumatic remedy, inhibit the proinflammatory transcription factor NF-kB. 2006;61(11):952-6. Search for the antiprostatic principle of stinging nettle (Urtica dioica) roots. www.drweil.com. Combined sabal and urtica extract compared with finasteride in men with benign prostatic hyperplasia: analysis of prostate volume and therapeutic outcome. Goetz P. [Treatment of benign prostate hyperplasia with nettle roots]. Lopatkin, N. A., Sivkov, A. V., Medvedev, A. View abstract. Look for freeze-dried extracts of the leaves, sold in capsules. Urologia. Antiproliferative effect on human prostate cancer cells by a stinging nettle root (Urtica dioica) extract. Purnak, T., Ozaslan, E., Beyazit, Y., and Haznedaroglu, I. C. Upper gastrointestinal bleeding in a patient with defective hemostasis successfully treated with ankaferd blood stopper. 2007;120(1265):U2803. Planta Med 1995;61(1):31-32. 2008;16(2):66-72. Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.. Effect of beta-sitosterol as inhibitor of 5 alpha-reductase in hamster prostate. Altern.Ther.Health Med. Oliver, F., Amon, E. U., Breathnach, A., Francis, D. M., Sarathchandra, P., Black, A. K., and Greaves, M. W. Contact urticaria due to the common stinging nettle (Urtica dioica)-- histological, ultrastructural and pharmacological studies. Proscar side effects can be pretty bad and may include long-term sexual dysfunction. Liebigs Ann Chem 1991;335-339. More M, Gruenwald J, Pohl U, Uebelhack R. A Rosa canina - Urtica dioica - Harpagophytum procumbens/zeyheri combination significantly reduces gonarthritis symptoms in a randomized, placebo-controlled double-blind study. Planta Med 1994;60(1):30-33. View abstract. View abstract. Freeze-dried preparations of nettle leaf are also available. Taking stinging nettle leaf preparations for 8-12 weeks seems to reduce blood sugar in people with type 2 diabetes. Touching the nettle plant can lead to an allergic rash. 1994;44(388):533-534. Drink 1 … Aqueous extract of Urtica dioica makes significant inhibition on adenosine deaminase activity in prostate tissue from patients with prostate cancer. Phytomedicine. 2003;89(1):47-53. View abstract. Therapeutic effects of stinging nettle (Urtica dioica) in women with hyperandrogenism. The leaves and stems of stinging nettle possess anti-inflammatory actions and have long been used to treat painful muscles and joints, eczema, arthritis, and gout, as well as anemia. There is currently no recommended dosage for stinging nettle, but if you are taking it for a specific condition like BPH, then it is advised to take 360 milligrams of root extract per day. Randall, C., Dickens, A., White, A., Sanders, H., Fox, M., and Campbell, J. Nettle sting for chronic knee pain: a randomised controlled pilot study. There is currently no recommended dose, because so many nettle products have varying amounts of active ingredients. 8-1-2011;14(15):775-779. 2010 Oct;7(10):3804-15. Pregnant women should avoid stinging nettle because its hormonal effects could lead to miscarriage. 1991;16(1):1-7. Taking stinging nettle might decrease how well the body gets rid of lithium. Schneider, T. and Rubben, H. [Stinging nettle root extract (Bazoton-uno) in long term treatment of benign prostatic syndrome (BPS). While generally regarded as safe, stinging nettle can cause side effects including mild stomach upset, fluid retention, sweating, diarrhea, and hives or an allergic rash (mainly from topical use). 2005;5(4):1-11. Br.J Dermatol. View abstract. Acute diuretic, natriuretic and hypotensive effects of a continuous perfusion of aqueous extract of Urtica dioica in the rat. 1999;26(12):2517-2522. In case of relief from allergies, 300 mg of the same is recommended twice a day. Child Dosage: No more than one capsule per day. Cai, T., Mazzoli, S., Bechi, A., Addonisio, P., Mondaini, N., Pagliai, R. C., and Bartoletti, R. Serenoa repens associated with Urtica dioica (ProstaMEV) and curcumin and quercitin (FlogMEV) extracts are able to improve the efficacy of prulifloxacin in bacterial prostatitis patients: results from a prospective randomised study. Read here to find out who is affected by these nettle tea side effects and how to mitigate them. FEBS Lett 1-8-1999;442(1):89-94. Nutritive tonic- restores the body and adds nutrients. Stinging nettle products come in dried or freeze-dried leaf form, extract, capsules, tablets, as well as a root tincture (suspension of the herb in alcohol), juice or tea. Namazi, N., Esfanjani, A. T., Heshmati, J., and Bahrami, A. The urticaria is accompanied by a stinging sensation lasting longer than 12 h. There Medications that cause sleepiness are called sedatives. 2017 Dec;83(18):1384-91. Part II: urticae radix. 1988;119(2):269-270. Rough, scaly skin on the scalp and face (seborrheic dermatitis). … Because stinging nettle may affect blood sugar, it could interfere with the management of diabetes. Hay fever. Precautions. View abstract. stinging nettle side effects Stinging nettle probably is safe with limited side effects. View abstract. 13. Vontobel HP, Herzog R, Rutishauser G, Kres H. [Results of a double-blind study on the effectiveness of ERU (extractum radicis Urticae) capsules in conservative treatment of benign prostatic hyperplasia]. Anti-microbial. Optimal doses of stinging nettle have not been set for any condition. Luczaj, L. and Szymanski, W. M. Wild vascular plants gathered for consumption in the Polish countryside: a review. Consult a healthcare provider or/and the labeling (if using manufactured stinging nettle supplements) for the correct dosage. Infections of the kidney, bladder, or urethra (urinary tract infections or UTIs). View abstract. All rights reserved. It is really important to intake the appropriate dose of stinging nettle herb the dosage depends on several factors such as the user’s age or health, and several other conditions. Medications for diabetes (Antidiabetes drugs) interacts with STINGING NETTLE. Pharm World Sci 1996;18(1):35-41. Stinging nettle may lead to minor side effects such as an upset stomach and sweating. Stinging nettle above ground parts seem to decrease blood pressure. Urtica dioica; urtica urens (Nettle). Stinging nettle was originally from northern Europe and Asia, and now grows worldwide as … Depurative– cleanses the blood, often helpful for skin and detoxifying. View abstract. Aust J Med Herbalism 1993;5(1):5-13. A., Walter, K., Schlefke, S., Avdeichuk, IuI, Golubev, G. V., Mel'nik, K. P., Elenberger, N. A., and Engelman, U. Gansser D and Spiteller G. Aromatase inhibitors from Urtica dioica roots. Sahin, M., Yilmaz, H., Gursoy, A., Demirel, A. N., Tutuncu, N. B., and Guvener, N. D. Gynaecomastia in a man and hyperoestrogenism in a woman due to ingestion of nettle (Urtica dioica). View abstract. Topical stinging nettle ointment is intended for the short-term treatment of dermatitisand other mild ski… View abstract. London: Churchill Livingstone, 2000. Stinging nettle can lower blood pressure, which means it could heighten the effect of blood pressure medications. Medications for high blood pressure (Antihypertensive drugs) interacts with STINGING NETTLE. Wagner H, Geiger WN, Boos G, and et al. Mittman P. Randomized, double-blind study of freeze-dried Urtica dioica in the treatment of allergic rhinitis. Early research suggests that using stinging nettle above ground parts at the first signs of hay fever symptoms may help provide relief. 2010;77(3):180-186. Early research suggests that taking a stinging nettle root preparation for about 4 months is not more effective than standard therapy for improving menstrual cycle conditions, oily skin, or acne in women with high testosterone levels. Anales de Bromatologia 1983;35(1):99-104. Other products containing stinging nettle root extract or a combination of stinging nettle root, saw palmetto lipoidal extract, pumpkin seed oil, lemon bioflavonoid, and beta-carotene don't seem to improve most BPH symptoms. J Evid Based Complementary Altern Med. Bakhshaee M, Mohammadpour AH, Esmaeili M, et al. Stinging Nettle Dosage. Nettle is available under the following different brand and other names: stinging nettle, and Urtica dioica. Obertreis, B., Ruttkowski, T., Teucher, T., Behnke, B., and Schmitz, H. Ex-vivo in-vitro inhibition of lipopolysaccharide stimulated tumor necrosis factor-alpha and interleukin-1 beta secretion in human whole blood by extractum urticae dioicae foliorum. 6. Phytother Res 2020;34(2):282-94. Studies indicate that the leaves can relieve joint pain when applied to painful areas of the skin. If you are looking out for prostate health, then 120 mg of stinging nettle root extract is recommended thrice a day. Do You Need More Vitamin D In The Winter? Combined extracts of Urtica dioica and Pygeum africanum in the treatment of benign prostatic hyperplasia: double-blind comparison of two doses. (check all that apply), What factors are most important to you? Pharmazie. Urtica dioica agglutinin: a plant lectin with antifungal properties. 2011;19(5):276-280. View abstract. Int.J Antimicrob.Agents 2009;33(6):549-553. Stinging nettle is fully effective after approximately 30 days of use. View abstract. Some medications used for diabetes include glimepiride (Amaryl), glyburide (DiaBeta, Glynase PresTab, Micronase), insulin, pioglitazone (Actos), rosiglitazone (Avandia), chlorpropamide (Diabinese), glipizide (Glucotrol), tolbutamide (Orinase), and others. Hryb, D. J., Khan, M. S., Romas, N. A., and Rosner, W. The effect of extracts of the roots of the stinging nettle (Urtica dioica) on the interaction of SHBG with its receptor on human prostatic membranes. Efficacy of a supportive therapy of allergic rhinitis by stinging nettle (Urtica dioica) root extract: a randomized, double-blind, placebo-controlled clinical trial. Onal S, Timur S, Okutucu B, Zihnioglu F. Inhibition of alpha-glucosidase by aqueous extracts of some potent antidiabetic medicinal herbs. View abstract. View abstract. Stinging nettle might have an effect like a water pill or "diuretic." Arthritis Res.Ther. View abstract. In fact, one reason to consider effective natural therapies such as stinging nettle and saw palmetto is that popular BPH drugs can cause erectile dysfunction and other negative side effects, while the natural supplements do not. Hill, N., Stam, C., and van Haselen, R. A. How Long Does Coronavirus Live On Surfaces? If you have diabetes, keep close track of your blood sugar when using stinging nettle. Nettle is used in many ways for many reasons. View abstract. Urologia. View abstract. Balzarini, J., Neyts, J., Schols, D., Hosoya, M., Van Damme, E., Peumans, W., and De Clercq, E. The mannose-specific plant lectins from Cymbidium hybrid and Epipactis helleborine and the (N-acetylglucosamine)n-specific plant lectin from Urtica dioica are potent and selective inhibitors of human immunodeficiency virus and cytomegalovirus replication in vitro. View abstract. Int Arch Allergy Appl.Immunol. Lab. Alternative Medicine Review 2007;12:280-284. J Ethnopharmacol 2000;73(1-2):95-100. You should not use the information on this website for diagnosing or treating a health problem or disease, or prescribing any medication or other treatment. Talk with your healthcare provider before using this product if you are taking lithium. View abstract. Improved glycemic control in patients with advanced type 2 diabetes mellitus taking Urtica dioica leaf extract: a randomized double-blind placebo-controlled clinical trial. Sokeland J. J Nat Prod. Complement Ther.Med. [12] A frequent cause of contact urticaria is skin exposure to the common stinging nettle (Urtica dioica). Eur.J.Emerg.Med. Medscape - Indication-specific dosing for stinging nettle, urtica dioica (nettle), frequency-based adverse effects, comprehensive interactions, contraindications, pregnancy & … 2017 Oct;22(4):603-608. Archives Internationales de Physiologie et de Biochimie 1988;96(1):31. BY MOUTH: Did you or will you purchase this product in-store or online? 2009;11(6):R192. Double-blind study with an extract of Radicus Urticae (ERU)]. Induction of insulin secretion by a component of Urtica dioica leave extract in perifused Islets of Langerhans and its in vivo effects in normal and streptozotocin diabetic rats. Kassen A, Berges R, Senge T, et al. View abstract. This combination seems to be comparable to the prescription medication finasteride for relieving symptoms of BPH, and it may be better tolerated. Although not all side effects are known, nettle is thought to be possibly safe when taken for a short period of time (no longer than 6 months). View abstract. University of Maryland Medical Center. View abstract. 2009;15(4):60-61. View abstract. Urologe A 2004;43(3):302-306. For nettle leaf, which will be freeze-dried, go for a daily total of 600mg split into two separate servings. Laboratory studies have shown that the effects of stinging nettle, in combination with saw palmetto or other herbs, are comparable to those of finasteride, a drug often prescribed for BPH. Stinging nettle above ground parts might decrease blood sugar. Osteoarthritis. or Healthy Lifestyle Brands. WebMD does not provide medical advice, diagnosis or treatment. View abstract. Safarinejad, M. R. Urtica dioica for treatment of benign prostatic hyperplasia: a prospective, randomized, double-blind, placebo-controlled, crossover study. View abstract. View abstract. View abstract. Results of a randomized, double-blind, placebo controlled multicenter study after 12 months]. SOURCES: Topical ointments and creams that contain stinging nettle are also available. © 2005 - 2019 WebMD LLC. Clin Exp Dermatol. Chrubasik, J. E., Roufogalis, B. D., Wagner, H., and Chrubasik, S. A comprehensive review on the stinging nettle effect and efficacy profiles. 5. Studies on the binding of Urtica dioica agglutinin (UDA) and other lectins in an in vitro epidermal growth factor receptor test. Durak I, Biri H, Devrim E, et al. Mol.Pharmacol. Lignans from the roots of Urtica dioica and their metabolites bind to human sex hormone binding globulin (SHBG). Planta Medica 1995;61:138-140. View abstract. View abstract. Baraibar CB, Broncano FJ, Lazaro-Carrasco MJ, and et al. Where did you or where do you plan to purchase this product? Marks L, Partin AW, Epstein JI, et al. View abstract. Follow the directions on the package label or use the lowest effective dose. 2014;2(7):153-160. View abstract. Engelmann U, Boos G, and Kres H. [Therapy of benign prostatic hyperplasia with Bazoton liquidum]. View abstract. Fortschr Med 1995;113(3):37-40. View abstract. Cabeza M, Bratoeff E, Heuze I, et al. View abstract. It gets its name from the fine hairs on its leaves and stems that release … View abstract. Acta Pol.Pharm. View abstract. Lichius, J. J., Lenz, C., Lindemann, P., Muller, H. H., Aumuller, G., and Konrad, L. Antiproliferative effect of a polysaccharide fraction of a 20% methanolic extract of stinging nettle roots upon epithelial cells of the human prostate (LNCaP). Taking stinging nettle leaf preparations by mouth might also reduce the need for pain medications. Clin Ther 1993;15(6):1011-1020. Rayburn, K., Fleischbein, E., Song, J., Allen, B., Kundert, M., Leiter, C., and Bush, T. Stinging nettle cream for osteoarthritis. Konieczynski, P. and Wesolowski, M. Water-extractable magnesium, manganese and copper in leaves and herbs of medicinal plants. This makes it hard to set a standard dose. Prospective study on 320 patients]. 2014;32:1149-1154. J Urol 2000;163:1451-6. Krystofova O, Adam V, Babula P, et al. Uncontrolled Blood Sugar: How Dangerous Is It? The other parts of the plant can be put into soups and dishes. May Reduce Inflammation. Most products on the market give you 500 mg per capsule. 2017 Nov;77(5):335-37. 2007;3:17. Stinging nettle capsules are usually offered in 300-milligram to 900-milligram formulations and are generally considered safe at these doses. The efficacy and safety of Urtica dioica in treating benign prostatic hyperplasia: a systematic review and meta-analysis. Mills S, Bone K. Principles and Practice of Phytotherapy. Bichu, Common Nettle, Feuille d’Ortie, Graine d’Ortie, Grande Ortie, Great Stinging Nettle, Nettle, Nettle Leaf, Nettle Seed, Nettle Worth, Nettles, Ortie, Ortie Brûlante, Ortie des Jardins, Ortie Dioïque, Ortie Méchante, Ortiga, Small Nettle, Stinging Nettles, Urtica, Urtica dioica, Urtica urens, Urticae Herba et Folium, Urticae Radix. Anti-allergic– reduces allergic symptoms via mast cell stabilization. Taking stinging nettle along with diabetes medications might cause your blood sugar to go too low. This could increase how much lithium is in the body and result in serious side effects. View abstract. Nettle Root Versus Stinging Nettle Practitioners of traditional herbal medicine practitioners have used the stinging nettle plant, also known as Urtica dioica to treat many disorders. [Urination disorders caused by prostatic hyperplasia. Dr. Weil Says: Freeze-dried stinging nettle may help relieve the symptoms of hay fever and other allergies. A summary of findings and risk-of-bias assessment. Ghalavand A, Motamedi P, Deleramnasab M, Khodadoust M. The effect of interval training and nettle supplement on glycemic control and blood pressure in men with Type 2 Diabetes. View abstract. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. This survey is being conducted by the WebMD marketing sciences department. Caliskaner Z, Karaayvaz M, Ozturk S. Misuse of a herb: stinging nettle (Urtica urens) induced severe tongue oedema. 2009;20(6):511-5. View abstract. Many studies have evaluated a particular combination product that contains stinging nettle and saw palmetto (PRO 160/120 by Willmar Schwabe GmbH). This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. Chrubasik, J. E., Roufogalis, B. D., Wagner, H., and Chrubasik, S. A. For treating arthritis, one study had success using fresh nettle leaves to "sting" the arthritic joint once daily.For allergy treatment, a dose of 300 mg of stinging nettle extract three times a day is sometimes suggested.For treating an enlarged prostate, studies have used various doses, such as 80 mg three times daily or 120 mg twice daily (in combination with other herbs). 2005;35(1):29-36. Risks and Side Effects of Stinging Nettle Freeze-dried stinging nettle may help relieve the symptoms of hay fever and other allergies. 2008;74(2):330-337. View abstract. View abstract. Clin Exp Obstet Gynecol 2013;40(1):141-143. Munchen: Zuckerscherdt;1992. Use caution if you have low blood pressure. A comprehensive review on nettle effect and efficacy profiles, Part I: herba urticae. The leaves and the stems have fine hairs that contain irritating chemicals, which are released upon contact with the skin. Side Effects. Simian immunodeficiency virus is susceptible to inhibition by carbohydrate-binding agents in a manner similar to that of HIV: implications for further preclinical drug development. 2017;2(1):33-40. Khalili N, Fereydoonzadeh R, Mohtashami R, Mehrzadi S, Heydari M, Huseini F. Silymarin, Olibanum, and Nettle, a mixed herbal formulation in the treatment of Type II Diabetes: a randomized, double-blind, placebo-controlled, clinical trial. Maor D, Little M. Skin contact with a stinging tree requiring intensive care unit admission. Stinging nettle above ground parts contain large amounts of vitamin K. Vitamin K is used by the body to help blood clot. CONDITIONS OF USE AND IMPORTANT INFORMATION: There is no safe and effective dose of stinging nettle for any medical purpose because no sufficiently powerful study has been conducted to find one. Nettle side effects. Did You Know Black Pepper Can Be Good For You. But there is insufficient scientific evidence to show that stinging nettle is effective for many of these disorders. Alt Med Rev 1998;3:140-3. Monograph. View abstract. Int J Basic Sci Med. Nettle (or stinging nettle) is a plant also known as Bichu, Feuille d'Ortie, Graine d'Ortie, Grande Ortie, Ortie, Ortiga, Urtica, and other names. Research studies of stinging nettle typically do not report dosages Stinging nettle root supplements typically supply 500-750 mg dosages Multi-ingredient formulas typically provide smaller dosages (360 mg) Enlarged prostate (benign prostatic hyperplasia or BPH). However, most supplements recommend 250-750 mg. View abstract. Complement Ther Med 1999;7(3):126-131. Eyi, E. G., Engin-Ustun, Y., Kaba, M., and Mollamahmutoglu, L. Ankaferd blood stopper in episiotomy repair. Diabetes. Dosage and parts used vary according to the condition being treated. View abstract. As for testosterone, this human-based study showed no difference in testosterone levels before, during, or after. Because of its diuretic effects, stinging nettle may also affect the way the body eliminates lithium. Clin. View abstract. 3. Randall C, Randall H, Dobbs F, et al. Anti-rheumatic– an umbrella term for an herb that helps musculoskeletal conditions with undefined mechanism. Complement Ther Med 2004;12:57-8. Planta Med 1997;63:529-32. View abstract. Stinging nettle also is used to treat osteoarthritis and sore muscles. IJPR 2017;16(Special Issue):112-118. Simões-Pires CA, Hmicha B, Marston A, Hostettmann K. A TLC bioautographic method for the detection of alpha- and beta-glucosidase inhibitors in plant extracts. Diabetes medications are also used to lower blood sugar. Van Parijs J, Broekaert WF, and Peumans WJ. Dried leaf, freeze-dried leaf, extract, capsules, tablets, and as root tincture (a solution of the herb in alcohol). It also can increase the effects of drugs for diabetes, possibly leading to low blood sugar (hypoglycemia). View abstract. Phytomedicine 1994;1:213-224. Edgcumbe, D. P. and McAuley, D. Hypoglycaemia related to ingestion of a herbal remedy. Randall, C., Meethan, K., Randall, H., and Dobbs, F. Nettle sting of Urtica dioica for joint pain--an exploratory study of this complementary therapy. View abstract. J Contemp Dent Pract 2010;11(1):E088-E094. Phytomedicine. 2008;15(4):236-237. Eur Urol 2000;37:735-41. . Stinging nettle is used orally and topically to relieve the pain of sprains, strains, tendinitis (also spelled tendonitis), and insect bites as well. J.Herb.Pharmacother. Koch, E. Extracts from Fruits of Saw Palmetto (Sabal serrulata) and Roots of Stinging Nettle (Urtica dioica): Viable Alternatives in the Medical Treatment of Benign Prostatic Hyperplasia and Associated Lower Urinary Tracts Symptoms. Christensen, R. and Bliddal, H. Is Phytalgic(R) a goldmine for osteoarthritis patients or is there something fishy about this nutraceutical? Stinging nettle (Urtica dioica) grows all over the world and blooms June through September, with pink and yellow flowers. Schottner M, Gansser D, Spiteller G, et al. Stinging nettle can act as a diuretic and may increase the effects of drugs that increase urination (diuretics). Your lithium dose might need to be changed. Fischer M and Wilbert D. [Efficacy testing of a phytopharmacon in the treatment of benign prostate hyperplasia (BPH)]. Patten G. Medicinal plant review: Urtica. Beyazit, Y., Kurt, M., Kekilli, M., Goker, H., and Haznedaroglu, I. C. Evaluation of hemostatic effects of Ankaferd as an alternative medicine. 2010;12(1):105. There is conflicting evidence about the effects of stinging nettle on symptoms of BPH. Krzeski, T., Kazon, M., Borkowski, A., Witeska, A., and Kuczera, J. Oelke, M, Berges R, Schläfke S, Burkart M. Fixed-dose combination PRO 160/120 of sabal and urtica extracts improved nocturia in men with LUTS suggestive of BPH: re-evaluation of four controlled clinical studies. Work with your doctor to determine the right dosage. View abstract. Pavone, C., Abbadessa, D., Tarantino, M. L., Oxenius, I., Lagana, A., Lupo, A., and Rinella, M. [Associating Serenoa repens, Urtica dioica and Pinus pinaster. Najafipour F, Rahimi AO, Mobaseri M, Agamohamadzadeh N, Nikoo A, Aliasgharzadeh A. 4 g whole herb steeped 10 minutes hot water, three to four times daily. On top of this, it will help provide nourishment for the fur that will leave their coat healthier than any type of store-bought conditioner. ©Copyright 2020 Healthy Lifestyle Brands, LLC. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you. Talk to your doctor before giving stinging nettle to a child, so the doctor can determine the proper dose. 2011;25(2):312-313. Effect of Bazoton, Harzol and Prosta-capsules]. Talk with your healthcare provider before using this product if you are taking lithium. View abstract. [Combination of Sabal and Urtica extract vs. finasteride in benign prostatic hyperplasia (Aiken stages I to II). 2010;77(1):43-51. Some medications for high blood pressure include captopril (Capoten), enalapril (Vasotec), losartan (Cozaar), valsartan (Diovan), diltiazem (Cardizem), Amlodipine (Norvasc), hydrochlorothiazide (HydroDiuril), furosemide (Lasix), and many others. Baykul, T., Alanoglu, E. G., and Kocer, G. Use of Ankaferd Blood Stopper as a hemostatic agent: a clinical experience. Pharmazie 1999;54(10):768-771. Effects of a saw palmetto herbal blend in men with symptomatic benign prostatic hyperplasia. Tahri, A., Yamani, S., Legssyer, A., Aziz, M., Mekhfi, H., Bnouham, M., and Ziyyat, A. People who are pregnant should not take nettle, and those who take diuretics or medication for blood pressure or diabetes should consult with a healthcare professional before using it. Consumerlab. Stinging nettle contains vitamin K and so could interfere with the anticoagulant drug, warfarin (Coumadin). Francois, K. O., Auwerx, J., Schols, D., and Balzarini, J. Randall, C. F. Stinging nettles for osteoarthritis pain of the hip. Bercovich, E. and Saccomanni, M. Analysis of the results obtained with a new phytotherapeutic association for LUTS versus control. Kianbakht S, Khalighi-Sigaroodi F, Dabaghian FH. Never apply stinging nettle to an open wound. The effect of nettle (Urtica dioica) supplementation on the glycemic control of patients with type 2 diabetes mellitus: a systematic review and meta-analysis. There are no guidelines for the appropriate use of stinging needle supplements. View abstract. This copyrighted material is provided by Natural Medicines Comprehensive Database Consumer Version. Bombardelli E and Morazzoni P. Urtica dioica L. Fitoterapia 1997;68(5):387-402. High levels of testosterone in women (hyperandrogenism). Information from this source is evidence-based and objective, and without commercial influence. J Clin Periodontol. Urologe A 1985;24:49-51. But overall, nettle is regarded as safe and well-tolerated, with very low risk for side effects or toxicity. Sign Up to Receive Our Free Coroanvirus Newsletter. Planta Med 2001;67(6):489-500. Stinging Nettle Dosage: Most products on the market give you 500 mg per capsule. 10-30-1981;123(44):1675-1676. Br.J Gen.Pract. Long-term efficacy and safety of a combination of sabal and urtica extract for lower urinary tract symptoms--a placebo-controlled, double-blind, multicenter trial. Arzneimittelforschung 1996;46(4):389-394. Lopatkin N, Sivkov A, Walther C, et al. MMW.Munch.Med Wochenschr. Kulze, A. and Greaves, M. Contact urticaria caused by stinging nettles. 1998;25(5):399-403. Quality and active ingredients in supplements may vary widely from maker to maker. The method of taking stinging nettle will vary depending on its intended use. Large amounts of stinging nettle above ground parts might cause sleepiness and drowsiness. Urologe B 1987;27:223-226. Stinging Nettle Side Effects In: Rutishauser G. Benigne Prostatahyperplasie. Comparison of therapeutic effectiveness in a one year double-blind study]. Effect of beta-sitosterol on transforming growth factor-beta-1 expression and translocation protein kinase C alpha in human prostate stromal cells in vitro. J.Ethnobiol.Ethnomed. However, studies involving allergies and prostate enlargement used doses of 300-600 mg of dried extract. Male-pattern baldness (androgenic alopecia). N.Z.Med.J. J Rheumatol. Randomized controlled trial of nettle sting for treatment of base-of-thumb pain. Cancer Biol Ther 2004;3:855-7. Stinging Nettle. Antiviral Res 1992;18(2):191-207. Warfarin (Coumadin) interacts with STINGING NETTLE. All rights reserved. Sold in many health food stores and pharmacies, stinging nettle is available as capsules, tinctures, teas, wax-based salves, and ointment. While these hairs, or spines, are painful to the touch, they can actually relieve pain as well, perhaps by lowering levels of inflammatory chemicals in the body or by interfering with the way the body transmits pain signals. View abstract. consumerlab.com/tnp.asp?chunkiid=21815, Stinging Nettle. Arthritis Res.Ther. Also, 3.3 grams of stinging nettle leaf has been taken three times daily for 8 weeks. Dosages of Nettle: Suggested Dosing. J R Soc Med 2000;93:305-9. View abstract. Zeitschrift für Phytotherapie 1989;10:175-178. World J Urol. Urologe B 1996;36:287-291. (check all that apply). 2013;59:1071-1076. Stinging nettle may also affect the sneezing and itching of hay fever, perhaps because the herb can reduce the amount of histamine the body releases from mast cells in response to an allergen. 2. There is no recommended dosage for stinging nettle. Any third party offering or advertising on this website does not constitute an endorsement by Andrew Weil, M.D. 2006;(2):12, 14-12, 19. Schneider H, Honold E, and Masuhr T. Treatment of benign prostatic hyperplasia with a combination plant preparation. Planta Med 2000;66:44-7. Ziaei R, Foshati S, Hadi A, et al. 1. Chrubasik S, Enderlein W, Bauer R, and Grabner W. Evidence for antirheumatic effectiveness of Herba Urticae dioicae in acute arthritis: A pilot study. Potential side effects of stinging nettle Stinging nettle may cause some minor side effects such as sweating and an upset stomach. World J Urol 2005;23:139-46. It is used to treat uterine bleeding, nosebleeds, gastrointestinal bleeding, poor circulation, an enlarged spleen, diabetes and other endocrine disorders, diarrhea and dysentery, asthma, lung congestion, rashes, and cancer, and as a general tonic. Schöttner M, Spiteller G, Gansser D. Lignans Interfering with 5alpha-dihydrotestosterone binding to human sex hormone-binding globulin. Every herb used medicinally comes with side effects. BJU Int 2000;86:439-42. Lichius JJ, Muth C. The inhibiting effects of Urtica dioica root extracts on experimentally induced prostatic hyperplasia in the mouse. Adult. Make a good strong tea from the leaves and allow it to cool completely. You can stop the treatment as soon as the inflammation has gone down. Van der Weijden, G. A., Timmer, C. J., Timmerman, M. F., Reijerse, E., Mantel, M. S., and van, der, V. The effect of herbal extracts in an experimental mouthrinse on established plaque and gingivitis. The effect of hydro alcoholic Nettle (Urtica dioica) extracts on insulin sensitivity and some inflammatory indicators in patients with type 2 diabetes: a randomized double-blind control trial. Monitor your blood sugar closely. Stinging nettle can also have a diuretic effect, thereby increasing urinary frequency. Stinging nettle is a plant in the genus Urtica that originated as a native shrub in colder regions of Europe and Asia and is now found worldwide. http://umm.edu/health/medical/altmed/herb/stinging-nettle, accessed April 21, 2014. Coming to the stinging nettle plant, you can brew tea from the dried leaves and flowers. Planta Med 1997;63:307-10. . Nettle is possibly effective for the listed uses. Stinging nettle is used in many forms, including as teas, tinctures, fluid extracts, and creams. Farzami B, Ahmadvand D, Vardasbi S, Majin FJ, Khaghani Sh. View abstract. Stinging nettle root appears to have different pharmacological effects than the leaves. But it's not known if this benefit of this product is due to stinging nettle, saw palmetto, or both ingredients. Anon. Comparison of finasteride (Proscar), a 5 alpha reductase inhibitor, and various commercial plant extracts in in vitro and in vivo 5 alpha reductase inhibition. J Ethnopharmacol. Inflammation is your body’s way of healing itself and fighting infections. Phytomedicine 1996;3(2):121-128. Planta Med 1990;56:44-7. Contact Dermatitis. But symptom improvement may depend on the specific stinging nettle product used. Dathe G and Schmid H. [Phytotherapy of the benign prostatic hyperplasia (BPH). Be sure to have your blood checked regularly. Dosages of 600 mg of freeze-dried nettle leaf have been used in a clinical trial for allergic rhinitis.91 Clinical trials for BPH have used aqueous extracts of U. dioica root in dosages of 360 mg daily over 6 months35 and methanol root extract in dosages of 600 to 1,200 mg daily for 6 to 9 weeks.2 Nettle leaf extract is traditionally available in the form of dried or frozen leaves, creams, ointments and pills. Lopatkin, N., Sivkov, A., Schlafke, S., Funk, P., Medvedev, A., and Engelmann, U. Efficacy and safety of a combination of Sabal and Urtica extract in lower urinary tract symptoms--long-term follow-up of a placebo-controlled, double-blind, multicenter trial. 4. This could increase how much lithium is in the body and result in serious side effects. Afr J Tradit Complement Alt Med 2016;13(2):143-50. View abstract. 1998;61(1):119-21. [corrected]. The use of herbs is a time-honored approach to strengthening the body and treating disease. [Toxicity study of Urtica dioica L. nettle's] . 2010;15(4):329-336. Natural Medicines Comprehensive Database (Consumer Version), naturaldatabaseconsumer.therapeuticresearch.com/nd/Search.aspx?rn=3&cs=NONMP&s=NDC&pt=100&id=664&fs=NDC&searchid=46189911, accessed April 21, 2014. The following are the medicinal actions of nettle leaf and a definition of each for more clarity. 2012;69(1):33-39. Int J Curr Res Aca Rev. Styptic– stops bleeding when applied to a wound. What factors influenced or will influence your purchase? For professional medical information on natural medicines, see Natural Medicines Comprehensive Database Professional Version.© Therapeutic Research Faculty . Complement Ther.Med. Hallwachs, O. For inflammation: When the inflammation begins, drink a few glasses of stinging nettle tea throughout the day. View abstract. Phytochem Anal. Klingelhoefer, S., Obertreis, B., Quast, S., and Behnke, B. Antirheumatic effect of IDS 23, a stinging nettle leaf extract, on in vitro expression of T helper cytokines. Phytomedicine 1997;4(2):105-108. Taking stinging nettle leaf preparations by mouth or applying it to the skin might reduce pain in people with osteoarthritis. View abstract. Animal studies show that stinging nettle can help lower blood sugar and blood pressure, but more research is needed to determine if the same effects occur in humans. It is still not clear why stinging nettle reduces BPH symptoms, but it is possible that it may affect testosterone and estrogen or act directly on the prostate. 2007;39(4):1137-1146. Results of an observational study of sabal extract WS 1473 and Urtica extract WS 1031 in the offices of urologists. Phytother.Res. Wagner H, Willer F, Samtleben R, and et al. Nettle root extract, derived from the stinging nettle plant, is a popular supplement for body builders, and considered a relatively safe supplement as well. Taking stinging nettle along with sedative medications might cause too much sleepiness. Warfarin (Coumadin) is used to slow blood clotting. Hirano, T., Homma, M., and Oka, K. Effects of stinging nettle root extracts and their steroidal components on the Na+,K(+)-ATPase of the benign prostatic hyperplasia. However, stinging nettle does not decrease prostate size as finasteride does. Some research suggests that taking this product by mouth can improve urinary tract symptoms in men with BPH. 2007;14(6):423-435. In the case of a urinary tract or bladder infection, you should start drinking stinging nettle tea … View abstract. Int.Urol.Nephrol. Planta Med. ADULTS Dosage and Administration. All information will be used in a manner consistent with the WebMD, Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Coronavirus in Context: Interviews With Experts. At this time there is not enough scientific information to determine the exact and appropriate range of doses for stinging nettle. Today, the roots of the plant are used to treat the urinary symptoms of benign prostatic hyperplasia (BPH). Stinging nettle might have an effect like a water pill or "diuretic." The Benefits & Side Effects of Nettle Leaf Tea. Int J Environ Res Public Health. 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